Crenolanib (CP-868596) 2.4LCrenolanib (CP 868596) is a potent and selective inhibitor of PDGFR? ? with Kd of 2. 1 nM 3. 2 nM in CHO cells, also potently inhibits FLT3, sensitive to D842V mutation not V561D mutation, >100 fold more selective for PDGFR than c Kit, VEGFR 2, TIE 2, FGFR 2, EGFR, erbB2, and Src.
TAK-901 is a novel inhibitor of Aurora A/B with IC50 of 21 nM/15 nM
inhibiting cellular processing of A
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Corning 384 Well White with Clear Flat Bottom Polystyrene NBS Microplate
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It is an inhibitor of p300 histone acetylatransferase
Dorzolamide HCl is a water-soluble
Nilotinib (AMN-107) is a selective Bcr-Abl inhibitor with IC50 less than 30 nM in Murine myeloid progenitor cells
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