Tanzisertib(CC-930) Economy Double Metric Scale 10mL CylindersCC 930 is kinetically competitive with ATP in the JNK dependent phosphorylation of the protein substrate c Jun and potent against all isoforms of JNK (Ki(JNK1) = 44 3 nM, IC50(JNK1) = 61 nM, Ki(JNK2) = 6. 2 0. 6 nM, IC50(JNK2) = 5 nM, IC50(JNK3) = 5 nM) and selective against MAP kinases ERK1 and p38a with IC50 of 0. 48 and 3. 4 ? M respectively.
5-fold more selective for CDK1/2/4/6 than CDK7
Lomerizine dihydrochloride is a relatively new L- and T-type calcium channel blocker used in the treatment of migraine
Sodium Carbonate is the disodium salt of carbonic acid with alkalinizing property
inhibits corpus luteal steroidogenesis
22µm polytetrafluoroethylene (PTFE) hydrophobic membrane to allow sterile gas exchange while preventing contamination
The material makes the chamber more resistant to chemicals
AZD3839 is a potent and selective BACE1 inhibitor with Ki of 26
Ertugliflozin is a potent and selective sodium-dependent glucose cotransporter 2 inhibitor with IC50 values of 0
demonstrating a 193-fold selectivity against Notch
Doramectin is a macrocyclic lactone derivative of ivermectin
hypoglycemic and hypolipidemic activities
radicals scavenger with an IC50 of 56
